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Some Sjogren's patients report that tirzepatide worsens dry mouth , a symptom they already struggle with
Most patients experience gradual improvement over time, though a minority may have persistent symptoms requiring dose adjustment or treatment review
Flow of patients through the trial Perkovic et al , NEJM 2024 The randomized participants had a mean age of 66.6 years
McGuireDKVan de WerfFArmstrongPWStandlEKoglinJGreenJBet al
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