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DIO mice Eighteen-week-old male C57BL/6 DIO mice (14 weeks on HFD, Research Diets), purchased from The Jackson Laboratory, were dosed with vehicle (5% DMSO and 0.5% Kollidon-30 in 100 mM sodium phosphate buffer) or TLC-2716 (0.3 or 1 mg per kg (body weight)) once daily by oral gavage for 3 weeks
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Free Radic Biol Med 53(3):447456
These delivery methods are not interchangeable
D., Petruch, F
Research on face and neck lipolysis describes this cell-membrane disruption as the core mechanism across injectable fat-reduction products
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