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Second, 5-amino-1mq appears to be highly selective

Carroll BJ, Piazza G, Goldhaber SZ

MOTSc: Mitochondriaderived peptide with AMPK activation and insulin sensitivity effects

With aging, muscle stem cell function gradually declines, showing reduced proliferation and fusion, leading to impaired regeneration-one of the key mechanisms underlying sarcopenia.In vitro experiments confirm that 5-amino-1mq significantly enhances the proliferation and fusion of muscle stem cells from aged mice

3 In diet-induced obesity mouse models, administration of 5-Amino-1MQ led to notable reductions in body weight, white adipose tissue mass, and adipocyte size, without observable adverse effects or changes in food intake

The design of these compounds mainly involves the replacement of the metal ion with rhodium, nickel, or zinc, or may have an inactive ligand attached, such as 4-ethylphenyl