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Key properties: Stimulates GH release from the pituitary (not the hypothalamus) Does not significantly raise cortisol or prolactin Short half-life (~2 hours) produces a sharp, pulsatile GH release Does not block somatostatin (the hormone that inhibits GH release) Selective for GH minimal effect on other hormones The selectivity is what makes ipamorelin the preferred GHRP for most protocols
The without-DAC version does not have this group its half-life is about 30 minutes, so it produces short, pulsatile GH peaks that more closely mimic the natural rhythm of growth hormone secretion by the pituitary
Stay well-hydrated, especially if experiencing any gastrointestinal side effects
Understanding this prevents the frustration of expecting one outcome while experiencing another
Two or three drinks can quietly add several hundred calories to a day you thought was on track
Even when coverage is available, it may come with restrictions and isn't always guaranteed long-term
