Muthukumar K, Rajakumar S, Sarkar MN, Nachiappan V
The Independent
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Understanding the connection between redox homeostasis, proteins that mediate redox regulation, and disease pathophysiology in ALS, may facilitate a better understanding of disease mechanisms, and lead to the design of better therapeutic strategies
FIGURE 4 As discussed above, epigenetic inheritance, especially DNA methylation and histone modifications, plays an important role in regulating chromatin structure and expression of key genes, and multiple epigenetic enzyme inhibitors can be seen as autophagic triggers
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