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doi: 10.3389/fphar.2020.00240 140 RandeniNBordigaMXuB
Front Microbiol 11:557143
Our study showed that CuCl 2 and Cu(OAc) 2 had significantly upregulated HaCaT cell expression of IL-1 and IL-8 at both the gene level and protein level
& Reisin, E
In HCC driven by obesity and nonalcoholic steatohepatitis, the downregulation of CPT2 leads to the accumulation of acylcarnitines, among which C18:1-carnitine enhances spheroid formation by HCC cells through STAT3 activation, indicating that the accumulation of acylcarnitine can promote the development of liver cancer [212]
We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig
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