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Researchers used the primary estimand to assess effects regardless of treatment discontinuation or rescue interventions
1 4 Behavioural Neuroscience Research Early experimental investigations reported increased appetitive sexual behaviour without significant alterations in general motor activity or other reproductive behaviours, suggesting a selective pharmacological action mediated through central melanocortin pathways
[8] [9] Currently, NHS England advises that GLP-1 receptor agonists should be prioritised for patients with type 2 diabetes due to supply constraints
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