Side effects Commonly reported side effects of this medication include: Nausea Diarrhea Vomiting Stomach pain Constipation Gastrointestinal issues Bloating Other potential side effects: Indigestion Dizziness Back pain Increased lipase or amylase Altered taste Nasopharyngitis (common cold) Passing gas Bloating Belching Gastroenteritis Decreased appetite Gastroesophageal reflux disease Upset stomach These symptoms often subside as your body adjusts to the medications
The simplest way to think about them is in two buckets: stomach symptoms during dose escalation, and a separate skin-sensation signal at the highest dose in Phase 3
UV exposure is another major variable: limited, controlled UV can augment and stabilize Melanotan II-induced tanning, while intense sun exposure increases the risk of burns and potential long-term skin damage on top of any drug-related risks
If you feel a wave of nausea coming on, try upping your water intake to ensure youre staying fully hydrated
The Bottom Line May 2026 Status Editorial note: This article is a news update covering FDA regulatory action as of May 2026
This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat)