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Even if you're not currently obese or diabetic, using GLP-1 medication under medical supervision can help prevent future health issues tied to weight gain and insulin resistance
For example, semaglutide 2.4 mg showed a mean change of -14.9% at 68 weeks vs -2.4% with placebo in one major trial
That is just because its backed by data that makes it a credible supplement
Gut hormones and appetite control: a focus on Pyy and Glp-1 as therapeutic targets in obesity
Managing Side Effects The combination is generally well tolerated, but most patients experience at least mild side effects in the first 8 weeks
Genetic variation in the GLP1R gene (such as the rs6923761 variant), the GIPR gene, and metabolic genes like FTO and MC4R influence how your body responds to these therapies
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