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LCACs also perturb Ca 2+ homeostasis in the cytoplasm and have been shown to disrupt myocardial contractility and electrophysiology, thereby inducing cardiomyopathy and arrhythmias [294]
However, in recent years, the Food and Drug Administration (FDA) has approved some of these medications for weight loss purposes
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doi:1056/nejmoa2301972 Center For Drug Evaluation And Research
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