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Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time

Additionally, it is crucial for the production of mood-regulating chemicals in the brain, making it vital for emotional health

My book "Don't B12 Deficient" walks through it

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Pregnancy Health B12 deficiencies in the early stages of pregnancy increase the risk of neural tube birth defects and low birthweights

Because the body is efficient at excreting excess B12 through urine, there is no established tolerable upper intake level (UL) for the vitamin