Home measuring equipment (syringes, droppers, kitchen scales) introduces enough variance that hitting 0.9% precisely is difficult to verify without analytical chemistry equipment
Environ Toxicol Pharmacol 58:1120 Brandt C, Gastens AM, Sun M, Hausknecht M, Lscher W (2006) Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats
Journal of Drug Delivery Science and Technology, 43 , 379-387
Their high monthly price also places pressure on payers, who may impose restrictions, prior authorizations, or step-therapy requirements that reduce access
Provider continuity - Will you see the same prescriber for follow-ups, or different providers each time
It reduces atherosclerotic plaque formation, inhibits the expression of vascular adhesion molecules, and prevents LDL-induced immune cell adhesion (2931)