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PMC 4508379
PMID: 15051321 Woltjer RL, Nghiem W, Maezawa I, Milatovic D, Vaisar T, Montine KS, Montine TJ
NNMT is expressed in some cancer cells, which makes interpretation of inhibition complex: effects could differ by cancer type or stage, and the data are largely from models rather than long-term human study
When used, monitoring of maternal vital signs and general condition can provide reassurance that no adverse reactions (like excessive hypotension from niacinamide) are occurring
A growing body of evidence shows that it may be helpful in treating depression, including in those who were previously unresponsive to antidepressants or those with the MTHFR gene mutation
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