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Biomedicines 12 , 1636 (2024)

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Nagashima et al

Allergen immunotherapy (desensitisation) is available on the NHS for selected patients with confirmed IgE-mediated allergy who have not achieved adequate control with standard therapy, and can provide long-term relief without the need for ongoing medication

However, this approach is limited by its high cost and invasiveness, potential need for reintervention for mechanical failure and/or battery re-placement, and side effects (Ventureyra, 2000)

In summary, we present a panoptic analysis of the role of mitochondrial metabolism in dictating sensitivity to 5FU, the most commonly used chemotherapy worldwide