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Drug Absorption: SNAC integrates into the lipid membrane to increase the uidity of the gastric epithelium, allowing the peptide to enter the systemic circulation through transcellular pathways
However, direct comparisons across trials should be interpreted cautiously because of differences in study design, duration, and patient populations
PubMed ID: 17018654 Raun K et al
It's a function of the peptide's pharmacokinetics and the enzyme it targets
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