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PT-141 represents a fundamentally different category of treatment

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GLP-1 is secreted by intestinal L-cells in response to food intake and promotes insulin secretion from pancreatic -cells, thereby playing a key role in regulating the blood glucose concentration 20,21,22,23

GLP-1 receptor agonists delay gastric emptying, increase satiety and have several pleiotropic actions such as improvements in low grade inflammation and endothelial dysfunction thereby stabilising atherosclerotic plaques [3]

Avoid excessive caffeine or alcohol, as these can contribute to dehydration

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