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To minimize this risk, providers may recommend tapering off gradually and maintaining healthy eating and exercise habits

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[3] GLP-1 Market Industry Trends and Global Forecasts 2024-2035: Over 150 GLP-1 Drug Candidates in Development for Multiple Indications, Type 2 Diabetes and Obesity Drive GLP-1 Drug Development Boom (Accessed July August 2025)

Incidence rate difference (IRD) and hazard ratio (HR) were estimated in the matched cohorts

S., Fung, L., Wong, K

A summary of approximate phases, based on trial data, is as follows: Weeks 14: Appetite suppression and early metabolic changes may begin Weeks 412: Noticeable weight loss may commence Weeks 1248+: Progressive weight reduction, continuing through the trial period at higher doses These timelines reflect phase 2 trial experience and may differ in real-world settings