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Clinical Nutrition, 23(5), 1043-1050
In humans, the CYP450 enzyme that predominately catalyses the formation of NAPQI is CYP2E1, although in vitro CYP3A4, CYP2D6 and CYP1A2 have also been implicated in the formation of the toxic metabolite [18,19,20]
Personally, weve had people who had to take a very, very small dose of just 50mg every other day until they worked with one of our dietitians to open up their pathways and clear toxins before they could use a traditional dose of 500mg
Made in Germany, vegan, free from fillers, non-GMO, sugar-free, lactose-free, gluten-free, gelatin-free, nanoparticle-free, excellent bioavailability due to gentle production technologies without heat generation and without additives such as magnesium stearate or flow agents like silica dioxide
Martos-Maldonado MC et al
These are both obtained through compounding pharmacies and can be very helpful
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