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Molecular dynamics simulations indicate that N-terminal extension stabilizes the alpha helix structure of IGF-1 LR3, enhancing its binding ability to IGF-1 receptors

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Stockholm, Sweden or Warner Graham Co., Cockeysville, MD, USA) was diluted with vehicle (0.9% NaCl) to a 15% (w/v) solution and administered IP at 1.75 g/kg, 5 minutes prior to testing