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Adequate calcium and vitamin D, resistance training, and avoiding very rapid weight loss are the practical steps

European Journal of Endocrinology (1998) 5

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Double-immunofluorescence staining of GLP-1R and -smooth muscle actin (-SMA) in kidney sections confirmed the absence of GLP-1R expression in VSMCs of Glp1r VSM/ mice (Figure 1M)

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this suggests that BBR may treat periodontal bone loss caused by estrogen deficiency by regulating the gut microbiota (72)