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Future studies should explore whether perioperative hydration protocols, electrolyte monitoring, or cardiovascular screening could help mitigate these risks while maximizing the benefits of GLP-1 agonists in orthopedic surgical populations

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Brain glutathione levelsa novel biomarker for mild cognitive impairment and Alzheimers disease

Emerging Safety Concerns Recent research has identified new safety considerations beyond traditional gastrointestinal effects

Collectively, this evidence is consistent with the hypothesis that semaglutides primary value in the context of cognitive health may lie in prevention rather than treatment, particularly for cognitive decline driven by vascular and metabolic dysfunctions