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Accordingly, individualized titration and patient education remain important in routine care
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Even at doses exceeding 200-fold its GH ED, Ipamorelin produced ACTH and cortisol levels statistically indistinguishable from those following GHRH administration
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Nevertheless, oxyntomodulin can be cleaved by DPP-4 in vitro (36, 56), and in animal studies, the anorectic effects of exogenous oxyntomodulin are increased after DPP-4 inhibition (56), while DPP-4-resistant oxyntomodulin analogs have been associated with improved glucose tolerance, reduced food intake, greater energy expenditure, and weight loss (57, 58)
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