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Are the risks within reasonable limits

While there are different definitions, I will define a plateau as no weight loss over a month or longer

Systemically, because it involves copper, there is a theoretical risk of copper overload with prolonged, high-dose use without proper cycling

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GLP-1 utilization and spending are expected to continue growing as more prescribers and patients embrace the popular injectable formulations of these treatments, and, while the oral option may attract patients previously hesitant to try GLP-1 therapies due to injection concerns, it is unlikely to surpass injectables in market share

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