United States In the U.S., DSIP is not approved by the Food and Drug Administration (FDA) for medical purposes
What they found: Melanotan II is 100 to 1000 more potent than native -MSH in melanocyte assays Cyclization preserves the active conformation longer than linear -MSH Activates all four functional melanocortin receptors (MC1R, MC3R, MC4R, MC5R) In vivo: visible pigmentation of lizard skin within hours, not days as with -MSH Why it matters: This is the foundational publication of Melanotan II
Optimal dosing, timing, route of administration, and duration of treatment for human bone healing have not been established for investigational peptides
American College of Lifestyle Medicine (ACLM)
There are also theoretical concerns around abnormal blood vessel growth, tissue-growth signaling, and tumor biology, especially for individuals with active cancer or a recent cancer history
How Does AOD 9604 Peptide Therapy Work