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This dual activity at related receptor systems is part of what distinguishes cagrilintide from selective amylin-only analogs

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Historical Background and Scientific Context Scientific interest in DSIP emerged during the twentieth century as researchers sought to better understand naturally occurring peptide messengers and their role in biological signalling systems

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J Am Chem Soc (2021) 143:76472

This polarity-dependent decrease in inhibition mediated by ALLO may have important implications for how we approach the memory deficits associated with anxiety disorders, which may prove to be amenable to therapeutic strategies targeting the expression and/or activity of GABA A Rs of the 42 subtype (346)