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In this study, we evaluated the effects of QCHS on the gut microbiota and metabolism in UC mice

Although, in the majority of cases, tinnitus is associated with audiometrically-detected hearing loss, it can also occur without measurable hearing decline and independently of outer hair cell (OHC) loss 12,13

Compared to sham-operated controls, progression occurred at a younger age, closely resembling the trajectory observed in human diabetes

The trial product estimand assumed participants adhere to their assigned treatment during the trial

Without maintenance sessions and consistent sun protection, gradual return to baseline is expected, particularly in Kollam's high-UV coastal environment

The heterogeneous oxidative profile observed across brain regions likely reflects intrinsic metabolic and cellular differences among neural structures