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Kinetic analysis of Arabidopsis GCL showed that the enzyme was inactivated by buthionine sulfoximine, a potent inhibitor of mammalian GCL, and used a random ter-reactant kinetic mechanism with a preferred order of binding for catalysis (Jez et al., 2004)

An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model

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Researchers also found that the decrease in lean muscle mass was not all from skeletal muscles, but from other body tissues, including the liver