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The same phenomenon was observed in the aortic tissues of aging mice after FOXO4-DRI treatment (Figures 6C,D)
doi: 10.1016/j.jcrc.2014.05.021 43 MicallefJ.SoeiroT.Jonville-BraA
Similarly, we have previously demonstrated that long-term treatment with twice-daily injection of a GHRH superanalog is only partially able to restore somatotroph hypoplasia and growth in the GHRH knockout (GHRHKO) mouse (2)
Despite that, in one study of rats and ligaments, good effects were observed when it was provided orally (1)
PMID 10416260
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