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Some small studies show modest lightening effects, but large randomized trials in diverse populations are lacking

If side effects occur, the most common are nausea, indigestion, flatulence, diarrhea, constipation, headache, and fatigue, which usually resolves within the first month of use

Ethics declarations Competing interests KGW and VJNB are co-founders and shareholders of Aprea Therapeutics AB, a company that develops novel p53-based cancer therapy

It helps break down chemicals, heavy metals, and drugs, making them easier for the body to eliminate

Some users combine it with other peptides like BPC-157 for enhanced recovery and healing effects

There is a notable exception that relates to acute glutathione depletion due to acetaminophen (paracetamol) overdose, as we shall see