Conventional pro-oxidant strategies In addition to antioxidant strategies, several pro-oxidant regulatory approaches have long been applied in both clinical and basic research
[1] Unlike fat-soluble vitamins that accumulate in body tissues, water-soluble vitamins are generally excreted through urine when consumed in excess
Budden KF, Gellatly SL, Wood DL, Cooper MA, Morrison M, Hugenholtz P, Hansbro PM (2017) Emerging pathogenic links between microbiota and the gut-lung axis
10.1038/s41590-023-01719-3 37 ZhangJ.GuoY.MakM.TaoZ
Notably, at six months, mean GSH levels in erythrocytes, plasma, and lymphocytes had increased by 30-35% in the high-dose group, which was significantly greater than the increases observed in the placebo group
No difference in the need for definitive therapy was observed