Overall, these subgroup analyses did not reveal meaningful heterogeneity in associations by obesity status, indicating no evidence of effect modification by obesity ( Supplementary Figures 4 , 5 )
I treat those reports as signals to investigate patterns, because correlation can hide multiple explanations
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Type 2 diabetes increasingly represents a risk factor associated not only to cardiometabolic pathologies but also to neurological conditions
Average weight loss over 68 weeks reaches 15-22% of starting body weight