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This delayed transit time can impact how and when your body absorbs oral medications, including certain antibiotics

These medications should be avoided by people who are pregnant or breastfeeding, those with a history of pancreatitis, and anyone with a personal or family history of medullary thyroid cancer or MEN2 syndrome

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The fatigue may be the result of reduced calorie intake while taking the medication it may ease as your body adapts

Retatrutide is an investigational triple agonist peptide (GIP, GLP-1, and glucagon receptor) currently under clinical development for the management of obesity and type 2 diabetes