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It is one of the most-studied compounds in dermatology and matrix-biology research literature, frequently referenced in pre-clinical models of extracellular-matrix remodelling and gene-expression studies

References Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y

Animal and ex-vivo human skin studies have reported increased collagen and elastin synthesis

Conditions including acute hepatitis, cirrhosis, non-alcoholic fatty liver disease (NAFLD), and liver cancer have all been associated with elevated serum B12

For intramuscular B12 injections, a needle with a gauge of 22-25 and a length of 1-1.5 inches is typically recommended

The end of July, an FDA advisory committee meets to weigh in on whether some should be allowed for pharmacy compounding