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For GHK-Cu, the best-supported claims come from topical and wound-related evidence, while injectable and systemic claims need more rigorous human data [2], [3], [8]

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18 The treatment protocol for TPE consists of removing and retaining a considerable volume of plasma, approximately 1 to 1.5 plasma volume, 17 and returning the necessary cellular components via a colloid or combination colloid/crystallization solution of either fresh frozen plasma (FFP) or albumin

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