The most common adverse events reported with oral semaglutide were mild-to-moderate transient gastrointestinal eventsa finding consistent with the known tolerability of other available GLP-1 receptor agonists
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Brown GC, Bolanos JP, Heales SJ, Clark JB
When properly stored, this product maintains its quality for up to 4 years from the manufacturing date
This is OUTSIDE the normal experience and clinical expertise of the average GP, hence the centralised service, and GPs do NOT have to sign prescriptions for this service
For example, administration of 2.4 mg/week of semaglutide (instead of 1 mg used in diabetics) for 68 weeks leads to average losses of 15% of initial body weight, approximately double that in type 2 diabetics (Figure 5A)