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There are several mechanisms by which semaglutide can reduce blood pressure, including: Reduced body fat Improved insulin sensitivity The excretion of sodium in urine, known as natriuresis Vasodilation Nephroprotective Clinical studies indicate that semaglutide may have renal protective effects, with chronic kidney disease patients experiencing significantly improved outcomes following a dosage of 1 mg/week

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A clinician may adjust the dose based on response, side effects, and medical judgment

DOI Sub-study reporting liver-fat results in fatty-liver disease (MASLD)

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Volume values characterize the mean volume of the circular area centered around the foveola, corresponding to the 6 mm ring of the circular grid defined by the Early Treatment Diabetic Retinopathy Study [23]