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Cytokines and other active mediators regulate the functional activity of neutrophils by activating multiple receptors on these cells, thereby initiating downstream signal transduction pathways

Ilic S, Drmic D, Franjic S, Kolenc D, Coric M, Brcic L, et al

Metallothioneins, the most important intracellular copper storage proteins, are also upregulated by GHK-Cu, providing an additional protective mechanism against copper-induced toxicity

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In summary, plant GSTs may participate in the establishment of resistance to virus infections, either in the presence or absence of oxidative stress (HR-type necrosis) but could also contribute to the limitation of oxidative stress during virus susceptibility, i.e., in systemic infections