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Clinical trials show that orforglipron can help people lose, on average, about 12% of their body weight

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Your physician should also assess for contraindications, including personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or history of severe gastrointestinal disease

Because compounded GLP-1 medications vary in quality and safety, medical oversight is essential for effective and responsible treatment

USA 102 , 1565315658 (2005)