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(Heart disease, in general, is the leading cause of death in the United States its responsible for one in five deaths, killing someone every 33 seconds.) Obesity is a major contributing factor to heart failure, so Kramer and his collaborators in the SUMMIT trial wanted to see if tirzepatide, a weight-loss drug already approved by the federal Food and Drug Administration, could help

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Gastric bypass surgery leads to a substantial elevation in GLP-1 levels, and antagonism of GLP-1 largely negates the postsurgical improvements observed in glucose-stimulated insulin secretion (Jirapinyo et al., 2018)

A Danish cohort study evaluated an online weight-loss program that combined behavioral support with individualized semaglutide dosing

Modulation of epithelial cell growth by intraepithelial gamma delta T cells