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Many report normal body temperature readings despite feeling freezing, with some noting that healthcare providers commented on how cold their hands felt during examinations

One telehealth provider reported their compounded semaglutide tolerates temperatures up to 95 degrees Fahrenheit for a maximum of 4 days, and up to 77 degrees for 15 days

Depending on the extent of dysregulation, this effect is shortor long-term, leading to fatigue and cognitive impairments over time

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Because traditional management strategies necessitate that the patient must be self-reliant for glucose monitoring and insulin delivery, periods when he or she cannot be as vigilant, such as while sleeping, can present problems