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The landmark PANTHEON trial, a 1-year multicenter RCT in 1,006 Chinese COPD patients, found that high-dose NAC (600 mg twice daily) reduced the rate of acute exacerbations by 22% compared to placebo (1.16 vs 1.49 exacerbations per year, p=0.0011) (Zheng et al., Lancet Respir Med, 2014) [44]
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Celiac disease isn't the same as gluten intolerance or gluten sensitivity
Supplements and topical actives are meant to enhance a lifestyle built on solid health foundations, not replace them
However, it is associated with a risk of liver injury in patients with primary biliary cholangitis (328), and significantly elevates LDL-cholesterol (306)
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