Lack of physical activity (sedentary lifestyle), poor blood circulation , dehydration (drinking insufficient amount of water), stress, irritability, anxiety , and depression are also associated with the development of RLS
3.2 Carnitine deficiency across the course of diet therapy Of the 47 patients with a normal free carnitine level at baseline prior to starting MAD, 18 (38.3%) patients developed free carnitine deficiency during the course of diet therapy
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