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When food enters the digestive system, GLP-1 is released and acts on multiple targets: it stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

The purpose of the FDA letter was to inform the National Association of Boards of Pharmacy (NABP) that during inspections the FDA was starting to notice compounders utilizing Semaglutide Acetate and Semaglutide Sodium (ie the salts) in substitute for Semaglutide (base)

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