Social pressure to eat heavily conflicts with slowed gastric emptying from incretin therapy
Particularly beneficial in patients with BMI 30 or 27 with comorbidities
works best combined with circadian hygiene (morning sunlight, consistent wake times), stress management, regular exercise, and anti-inflammatory nutrition for holistic longevity support
Many individuals use GLP-1 medications such as Ozempic for type 2 diabetes
Receptor activation triggers adenylyl cyclase signaling, elevating intracellular cAMP, which activates protein kinase A (PKA) and subsequently the MITF (melanocyte-inducing transcription factor) pathway
My research published with Professor Carel Le Roux and Dr Faisal Almohaileb in Diabetes, Obesity and Metabolism found that patients reduced their alcohol intake from an average of 12 to 4 units a week