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129 Preclinical studies in various PD animal models indicate that GLP-1RAs such as liraglutide, semaglutide, and lixisenatide promote dopamine synthesis and elevate striatal dopamine levels, thereby conferring neuroprotection to dopaminergic neurons

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Local epigenetic modifications, including histone demethylation, directly promote pathogenic Th17 generation at the transcriptional level (39)

Bibcode:2006JThBi.238..416S

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