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This specific property has become the focus of numerous research strategies, such as the development of senolytic agents like FOXO4-DRI, which selectively disrupt the FOXO4p53 interaction, thereby enabling the targeted elimination of dysfunctional cells

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10.1007/s12035-014-9070-5 Mol

This results in abnormal metabolism of carbohydrates and increased glucose levels, which, in turn, can promote increased intracellular glucose metabolism, leading to oxidative stress (Ding et al., 2007), kallikrein-bradykinin activation (Campbell et al., 2010), and secretion of inflammatory cytokines (Nishikawa et al., 2000)

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NAD supports cellular vitality, while EGF helps encourage skin renewal and a firmer-looking texture