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Nrf2 is released from the Nrf2Keap1 system and then translocates to the cell nucleus, where it combines with small musculoaponeurotic fibrosarcoma (sMAF) proteins to form heterodimers

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In prediabetic status, increased blood glucose level stimulates the pancreatic islets to produce more insulin, leading to endogenous hyperinsulinemia in the human body

Wang D, Fei B, Halig LV, et al

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