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The medications in this class include semaglutide, sold as Ozempic for diabetes and Wegovy for weight loss, and tirzepatide, sold as Mounjaro for diabetes and Zepbound for weight management

This is based on the results of two clinical trials, which measured the medications effectiveness over the first four weeks and beyond

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Melasma risk factors exist including

For people who experience withdrawal effects or weight regain after stopping GLP-1 therapy , the amount of muscle preserved during treatment directly influences their trajectory

This overlap highlights their promise as pharmacological analogues of exercise, and underscores the need for biomarker-driven, disease-specific trials to establish whether GLP-1RAs can deliver durable disease modification across the spectrum of neurodegenerative diseases