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OR10-03 Murine bimagrumab co-administration with incretin agonists results in additive efficacy and superior quality weight loss in the mouse diet-induced obesity model

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For example, Trulicity is administered as a once-weekly injection and is FDA-approved for type 2 diabetes management, not weight lossthough some patients experience weight reduction as a side effect

(ADA 2024) gave cagrilintide and tirzepatide together to obese rats

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28 Oral administration does not appear to diminish the glucose-lowering or weight-lowering efficacy of semaglutide, 29 with oral semaglutide comparing favorably when studied against the SGLT-2 inhibitor empagliflozin