Noveltreat is also used in the treatment of Obesity or overweight conditions, alongside diet and exercise, particularly in adults with weight-related health complications such as heart disease
A GH pulse from the pituitary travels to the liver and peripheral tissues, where it drives the production of IGF-1 (insulin-like growth factor 1), the mediator responsible for most of GHs anabolic and recovery-related effects
As more data becomes available, these innovations may shift treatment initiation earlier, with a stronger emphasis on weight and cardiovascular outcomes alongside glucose control
The 64-week study enrolled 307 adults with obesity or overweight plus at least one weight-related comorbidity
doi: 10.1001/jamainternmed.2013.2720 221 KnapenLMvan DalemJKeulemansYCvan ErpNPBazelierMTDe BruinMLet al
MHRA-approved alternatives for weight management include semaglutide 2.4 mg (Wegovy), tirzepatide (Mounjaro), orlistat, and naltrexone/bupropion (Mysimba)